Structure of PDB 6twb Chain A Binding Site BS02
Receptor Information
| >6twb Chain A (length=238) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] |
| IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVE SPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLE TTVGYGDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKI PLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVW HLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV |
Ligand information
| >6twb Chain B (length=10) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] |
| CVNIMCCRCP |
Receptor-Ligand Complex Structure
| Global view | Local view | Structure summary | ||||||||
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Enzymatic activity
| Catalytic site (original residue number in PDB) | H57 D102 K192 G193 D194 S195 |
| Catalytic site (residue number reindexed from 1) | H44 D93 K185 G186 D187 S188 |
| Enzyme Commision number | 3.4.21.27: coagulation factor XIa. |
Gene Ontology
| Molecular Function | |
|---|---|
| GO:0004252 | serine-type endopeptidase activity |
