Structure of PDB 6tho Chain A Binding Site BS02

Receptor Information

>6tho Chain A (length=220) Species: 103690 (Nostoc sp. PCC 7120 = FACHB-418) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GPHMQTLTLSPNLIGFNSNEGEKLLLTSRSREDFFPLSMQFVTQVNQAYC
GVASIIMVLNSLGINAPETAQYSPYRVFTQDNFFSNEKTKAVIAPEVVAR
QGMTLDELGRLIASYGVKVKVNHASDTNIEDFRKQVAENLKQDGNFVIVN
YLRKEIGQERGGHISPLAAYNEQTDRFLIMDVSRYKYPPVWVKTTDLWKA
MNTVDSVSQKTRGFVFVSKT

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

6tho Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6tho Structural and Biophysical Analysis of the Phytochelatin-Synthase-Like Enzyme from Nostoc sp. Shows That Its Protease Activity is Sensitive to the Redox State of the Substrate.
Resolution	1.09 Å
Binding residue (original residue number in PDB)	D30 N136 Q139 N142
Binding residue (residue number reindexed from 1)	D33 N139 Q142 N145
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.3.2.15: glutathione gamma-glutamylcysteinyltransferase.

Gene Ontology

	Molecular Function
GO:0016740	transferase activity
GO:0016756	glutathione gamma-glutamylcysteinyltransferase activity
GO:0046872	metal ion binding

	Biological Process
GO:0010038	response to metal ion
GO:0046938	phytochelatin biosynthetic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:6tho, PDBe:6tho, PDBj:6tho
PDBsum	6tho
PubMed	35377603
UniProt	Q8YY76

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