Structure of PDB 6tce Chain A Binding Site BS02

Receptor Information
>6tce Chain A (length=123) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPAVKRLLGWKDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPS
KCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFP
FGSKQKEVCINPYHYKRVESPVL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6tce Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6tce Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes.
Resolution2.92 Å
Binding residue
(original residue number in PDB)		C65 C110 C122 H127
Binding residue
(residue number reindexed from 1)		C52 C97 C109 H114
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005667 transcription regulator complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6tce, PDBe:6tce, PDBj:6tce
PDBsum6tce
PubMed33510867
UniProtQ99717|SMAD5_HUMAN Mothers against decapentaplegic homolog 5 (Gene Name=SMAD5)

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