Structure of PDB 6s07 Chain A Binding Site BS02

Receptor Information
>6s07 Chain A (length=303) Species: 471852 (Thermomonospora curvata DSM 43183) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMPSFDFDIPRRSPQEIAKGMVAIPGGTFRMGGEDPDAFPEDGEGPVRTV
RLSPFLIDRYAVSNRQFAAFVKATGYVTDAERYGWSFVFHAHVAPGTPVM
DAVVPEAPWWVAVPGAYWKAPEGPGSSITDRPNHPVVHVSWNDAVAYATW
AGKRLPTEAEWEMAARGGLDQARYPWGNELTPRGRHRCNIWQGTFPVHDT
GEDGYTGTAPVNAFAPNGYGLYNVAGNVWEWCADWWSADWHATESPATRI
DPRGPETGTARVTKGGSFLCHESYCNRYRVAARTCNTPDSSAAHTGFRCA
ADP
Ligand information
Ligand IDCU1
InChIInChI=1S/Cu/q+1
InChIKeyVMQMZMRVKUZKQL-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cu+]
FormulaCu
NameCOPPER (I) ION
ChEMBL
DrugBank
ZINC
PDB chain6s07 Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6s07 Structure of formylglycine-generating enzyme in complex with copper and a substrate reveals an acidic pocket for binding and activation of molecular oxygen.
Resolution1.04 Å
Binding residue
(original residue number in PDB)		C269 C274
Binding residue
(residue number reindexed from 1)		C270 C275
Annotation score1
Enzymatic activity
Enzyme Commision number 1.8.3.7: formylglycine-generating enzyme.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0120147 formylglycine-generating oxidase activity
GO:1903136 cuprous ion binding
Biological Process
GO:0018158 protein oxidation
GO:0043687 post-translational protein modification

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Molecular Function
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Biological Process
External links
PDB RCSB:6s07, PDBe:6s07, PDBj:6s07
PDBsum6s07
PubMed31588272
UniProtD1A7C3|FGE_THECD Formylglycine-generating enzyme (Gene Name=Tcur_4811)

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