Structure of PDB 6ryo Chain A Binding Site BS02

Receptor Information
>6ryo Chain A (length=155) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITS
HRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNLFMQVAISLL
FAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIA
LLKDT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6ryo Chain A Residue 217 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6ryo Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin.
Resolution1.924 Å
Binding residue
(original residue number in PDB)		H0 H2
Binding residue
(residue number reindexed from 1)		H1 H3
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.23.36: signal peptidase II.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ryo, PDBe:6ryo, PDBj:6ryo
PDBsum6ryo
PubMed31919415
UniProtQ6GHN9|LSPA_STAAR Lipoprotein signal peptidase (Gene Name=lspA)

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