Structure of PDB 6rwg Chain A Binding Site BS02

Receptor Information
>6rwg Chain A (length=157) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNAATETLLVQN
ANPDCKTILKALGPGATLEEMMTACQGVGGPGHKARVLAEAMSQVTNPAT
IMIQKGNFRNQRKTVKCFNCGKEGHIAKNCRAPRKKGCWKCGKEGHQMKD
CTERQAN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6rwg Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6rwg The HIV-1 maturation inhibitor, EP39, interferes with the dynamic helix-coil equilibrium of the CA-SP1 junction of Gag.
ResolutionN/A
Binding residue
(original residue number in PDB)		C138 C141 H146 C151
Binding residue
(residue number reindexed from 1)		C138 C141 H146 C151
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:6rwg, PDBe:6rwg, PDBj:6rwg
PDBsum6rwg
PubMed32717487
UniProtP12493|GAG_HV1N5 Gag polyprotein (Gene Name=gag)

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