Structure of PDB 6r64 Chain A Binding Site BS02

Receptor Information
>6r64 Chain A (length=145) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFMHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYII
ERLVDSGVSQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRL
KMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6r64 Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Resolution2.64 Å
Binding residue
(original residue number in PDB)
W31 P33 R97 L98 R120
Binding residue
(residue number reindexed from 1)
W33 P35 R99 L100 R122
Binding affinityPDBbind-CN: Kd=2.2nM
Enzymatic activity
Enzyme Commision number 3.1.21.-
External links
PDB RCSB:6r64, PDBe:6r64, PDBj:6r64
PDBsum6r64
PubMed31724709
UniProtP24200|MCRA_ECOLI Type IV methyl-directed restriction enzyme EcoKMcrA (Gene Name=mcrA)

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