Structure of PDB 6qie Chain A Binding Site BS02

Receptor Information
>6qie Chain A (length=703) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTTAKQAEAVEDSDINPWTGQRHSERYFKILKARRKLPVNKQRQEFLDLY
HNNQILVFVGETGSGKTTQIPQYVLYDELPHQTGKLIACTQPRRVAAMSV
AQRVADELDVKLGEEVGYSIRFENKTSSKTLLKYMTDGQLLREAMHDRDM
SRYSCIILDEAHERTLATDILMALLKQLSERRKDLKIIVMSATLDAQKFQ
SYFFNAPLLAVPGRTHPVEIFYTPEAERDYVEAAIRTVLQIHACEPEGDI
LLFLTGEEEIEDACRRISLEVDEMIRESDAGPMSVYPLYGTLPPHQQQRI
FEKAPQPFRPGGRPGRKCIVATNIAETGLTIDGIVYVVDPGFSKQKIYNP
RTRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFKKELIEQTY
PEILRSNLSNTVLELKKLGVEDLVHFDLMDPPAPETMMRALEELNYLACL
DDDGELTPLGNLASEFPLDPALAVMLISSPEFYCSNEILSITSLLSVPQI
WVRPANARKRADEMKAQFAHPDGDHLTLLNAYHAYKGAEARGEDMKKWCH
EHFLSYRHLSSADNVRAQLKKIMETHGIELVSTPFHDKNYYTNIRRALLA
GFFMQVAMRESSNSKVYKTVKDEQLVLIHPSTTVTTPYEWVVYNEFVLTT
KQYVRTVTNIRPEWLLEIAPVYYDLSTFQKGEIKNALTRVAEKIRRQQAM
KAS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6qie Chain A Residue 817 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6qie Structural basis for RNA translocation by DEAH-box ATPases.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		T126 E219
Binding residue
(residue number reindexed from 1)		T67 E160
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Cellular Component
GO:0005681 spliceosomal complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6qie, PDBe:6qie, PDBj:6qie
PDBsum6qie
PubMed30828714
UniProtG0RY84

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