Structure of PDB 6q99 Chain A Binding Site BS02

Receptor Information
>6q99 Chain A (length=201) Species: 1980456 (Orthohantavirus andesense) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPMEKYREIHQRVRDLAPGTVSALECIDLLDRLYAVRHDLVDQMIKHDWS
DNKDVERPIGQVLLMAGIPNDIIQGMEKKIIPNSPSGQVLKSFFRMTPDN
YKITGNLIEFIEVTVTADVSRGIREAKIKYEGGLQFVEHLLETESRKGNI
PQPYKITFSVVAVKTDGSNISTQWPSRRNDGVIQHMRLVQADINYVREHL
I
Ligand information
Ligand IDMN3
InChIInChI=1S/Mn/q+3
InChIKeyMMIPFLVOWGHZQD-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Mn+3]
FormulaMn
NameMANGANESE (III) ION
ChEMBL
DrugBank
ZINC
PDB chain6q99 Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6q99 Specific inhibition of a diverse set of segmented negative strand viruses by a single molecule
Resolution2.951 Å
Binding residue
(original residue number in PDB)		E54 D97
Binding residue
(residue number reindexed from 1)		E56 D99
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.1.-.-
External links
PDB RCSB:6q99, PDBe:6q99, PDBj:6q99
PDBsum6q99
PubMed
UniProtQ9E005|L_ANDV RNA-directed RNA polymerase L

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