Structure of PDB 6pt2 Chain A Binding Site BS02

Receptor Information
>6pt2 Chain A (length=397) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TMADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKL
EDKSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTR
NAYIQKYLRSASSLALAIAITALYSAVCAVGLLGNVLVMFVIVRYTKMKT
ATNIYIFSLALAGALATSTLPFQSADYLMETWPFGELLCKAVLSIDYYSM
FTSIFTLTMMCVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVP
IMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVC
YGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVVAFVVCWAPIHIFVI
VWTLVDIDRRDPLVVAALHLCIALGYINSSLNPVLYAFLDKNFKRCF
Ligand information
Receptor-Ligand Complex Structure
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PDB6pt2 Elucidating the active delta-opioid receptor crystal structure with peptide and small-molecule agonists.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		F280 W284 L300
Binding residue
(residue number reindexed from 1)		F348 W352 L368
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004985 G protein-coupled opioid receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0038046 G protein-coupled enkephalin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pt2, PDBe:6pt2, PDBj:6pt2
PDBsum6pt2
PubMed31807708
UniProtP41143|OPRD_HUMAN Delta-type opioid receptor (Gene Name=OPRD1)

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