Structure of PDB 6pim Chain A Binding Site BS02

Receptor Information
>6pim Chain A (length=200) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQA
PEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQ
VVVTVKDMNDNAPTIEIRGIGDVAEETAVALVQVSDRDEGENAAVTCVVA
GDVPFQLRQASEKKKYFLQTTTPLDDYTIEIVAVDSGNPPLSSTNSLKVQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6pim Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6pim Identification of an adhesive interface for the non-clustered delta 1 protocadherin-1 involved in respiratory diseases.
Resolution3.05 Å
Binding residue
(original residue number in PDB)		N324 N326 D364 D366 N370 D423
Binding residue
(residue number reindexed from 1)		N109 N111 D136 D138 N142 D185
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pim, PDBe:6pim, PDBj:6pim
PDBsum6pim
PubMed31583286
UniProtQ08174|PCDH1_HUMAN Protocadherin-1 (Gene Name=PCDH1)

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