Structure of PDB 6pau Chain A Binding Site BS02

Receptor Information
>6pau Chain A (length=361) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAIEPDKDNVRQEPYSLPQGFMWDTLDLSDAEVLKELYTLLNENYVEDDD
NMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAIPANIRI
YDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGV
VLPKPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLYRLPDVTKT
SGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTF
VVESPNGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHTETPLLDLM
SDALILAKSKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCPG
TDSEKVGLVLQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6pau Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6pau NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle.
Resolution1.93 Å
Binding residue
(original residue number in PDB)		R255 S256 K257 V259
Binding residue
(residue number reindexed from 1)		R120 S121 K122 V124
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.97: glycylpeptide N-tetradecanoyltransferase.
Gene Ontology
Molecular Function
GO:0004379 glycylpeptide N-tetradecanoyltransferase activity
Biological Process
GO:0006499 N-terminal protein myristoylation

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:6pau, PDBe:6pau, PDBj:6pau
PDBsum6pau
PubMed32103017
UniProtO60551|NMT2_HUMAN Glycylpeptide N-tetradecanoyltransferase 2 (Gene Name=NMT2)

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