Structure of PDB 6p4f Chain A Binding Site BS02

Receptor Information
>6p4f Chain A (length=435) Species: 273063 (Sulfurisphaera tokodaii str. 7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSVYLRYFKGLILSDAYAPGLKWSDELKAYSALAFKYRDVRKYFLEKEIE
VEENVIDSLPFPLIKDKIELRDYQAEAVKAWLKEKRGIIVLPTGAGKTQV
ALKIVSIMKVATLIVVPTIDLITQWKERINKYLDFDPGIIGGGEDSLKGI
TVITYDSAYTRAEELGNKFPLLIFDEVHHLPSEGYSIMAQLFASPYRLGL
TATPERDDGKHELYPILVGPIVYRKSVEELAGKYIAKYKIKKLYVSLTNE
EKKRYDGLRKKLKDFLSSRGLKLQNLDDFHRLVKLAAKDKEAREALLAWH
ESLNIAVNSQSKIEKLREILQEYKNEKIIVFTRDTQMAYRISKTFLIPVV
TYKTDKDEREEILQKFRDGEYRVIVASTVFDEGVDVPDATLAIVMGGYGT
KRQFLQRLGRILRKKDKEALLIEIVTKGTADYRLS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6p4f Structural basis of the XPB helicase-Bax1 nuclease complex interacting with the repair bubble DNA.
Resolution3.55 Å
Binding residue
(original residue number in PDB)		T117 I118 G140 G141 T153 S156 V282 K283 A286 R292 L295 D333 T334 Y351 S376 V378
Binding residue
(residue number reindexed from 1)		T118 I119 G141 G142 T154 S157 V283 K284 A287 R293 L296 D334 T335 Y352 S377 V379
Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016853 isomerase activity
GO:0140097 catalytic activity, acting on DNA
Biological Process
GO:0006281 DNA repair
GO:0071103 DNA conformation change

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Molecular Function
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Biological Process
External links
PDB RCSB:6p4f, PDBe:6p4f, PDBj:6p4f
PDBsum6p4f
PubMed32986831
UniProtQ970I2|XPB2_SULTO DNA 3'-5' translocase XPB2 (Gene Name=xpb2)

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