Structure of PDB 6ojf Chain A Binding Site BS02

Receptor Information
>6ojf Chain A (length=188) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGMQSATVGIDVKDWPIQIR
DKRKRDLVLNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAM
KPWLFNIKARASSSPVILVGTHLDVSDEAQRAACMSKITKELLNKRGFPA
IRDYHFVNATEESDALAKLRKTIINESLNFKIRDQLVV
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6ojf Chain A Residue 1603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ojf Structural basis for conformational plasticity in the GTPase domain of the Parkinson's disease-associated protein LRRK2
Resolution1.6 Å
Binding residue
(original residue number in PDB)		M1409 T1410 Y1415
Binding residue
(residue number reindexed from 1)		M78 T79 Y84
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
3.6.5.-
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6ojf, PDBe:6ojf, PDBj:6ojf
PDBsum6ojf
PubMed
UniProtQ5S007|LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 (Gene Name=LRRK2)

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