Structure of PDB 6ogz Chain A Binding Site BS02

Receptor Information
>6ogz Chain A (length=1082) Species: 28875 (Rotavirus A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKYNLILSEYLSFIYNSQSAVQIPIYYSSNSELENRCIEFHSKCLENSKN
GLSLKKLFVEYSDVIENATLLSILSYSYDKYNAVERKLVKYAKGKPLEAD
LTVNELDYENNKITSELFPTAEEYTDLLMDPAILTSLSSNLNAVMFWLEK
HENDVAEKLKIYKRRLDLFTIVASTVNKYGVPRHNAKYRYEYEVMKDKPY
YLVTWANSSIEMLMSVFSHEDYLIARELIVLSYSNRSTLAKLVSSPMSIL
VALVDINGTFITNEELELEFSNKYVRAIVPDQTFDELKQMLDNMRKAGLT
DIPKMIQDWLVDCSIEKFPLMAKIYSWSFHVGFRKQKMLDAALDQLKTEY
TEDVDDEMYREYTMLIRDEVVKMLEEPVKHDDHLLQDSELAGLLSMSSAS
NGESRQLKFGRKTIFSTKKNMHVMDDMANGRYTPGIIPPVNVDKPIPLGR
RDVPGRRTRIIFILPYEYFIAQHAVVEKMLIYAKHTREYAEFYSQSNQLL
SYGDVTRFLSNNSMVLYTDVSQWDSSQHNTQPFRKGIIMGLDMLANMTND
ARVIQTLNLYKQTQINLMDSYVQIPDGNVIKKIQYGAVASGEKQTKAANS
IANLALIKTVLSRISNKYSFATKIIRVDGDDNYAVLQFNTEVTKQMVQDV
SNDVRETYARMNTKVKALVSTVGIEIAKRYIAGGKIFFRAGINLLNNEKK
GQSTQWDQAAVLYSNYIVNRLRGFETDREFILTKIMQMTSVAITGSLRLF
PSERVLTTNSTFKVFDSEDFIIEYGTTDDEVYIQRAFMSLSSQKSGIADE
IAASSTFKNYVSRLSEQLLFSKNNIVSRGIALTEKAKLNSYAPISLEKRR
AQISALLTMLQKPVTFKSSKITINDILRDIKPFFTVNEAHLPIQYQKFMP
TLPDNVQYIIQCIGSRTYQIEDDGSKSAISRLISKYSVYKPSIEELYKVI
SLHENEIQLYLISLGIPKIDADTYVGSKIYSQDKYRILESYVYNLLSINY
GCYQLFDFNSPDLEKLIRIPFKGKIPAVTFILHLYAKLEVINHAIKNGSW
ISLFCNYPKSEMIKLWKKMWNITSLRSPYTNA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ogz In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		A400 S401 F416 T418 I462 F463 K485 S495 Q496 S497 G592 E593 K594 K597 K701 T762 S792 S793 N1000
Binding residue
(residue number reindexed from 1)		A399 S400 F415 T417 I461 F462 K484 S494 Q495 S496 G591 E592 K593 K596 K700 T761 S791 S792 N999
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0019079 viral genome replication
Cellular Component
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ogz, PDBe:6ogz, PDBj:6ogz
PDBsum6ogz
PubMed31101900
UniProtG0YZJ9

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