Structure of PDB 6ogy Chain A Binding Site BS02

Receptor Information
>6ogy Chain A (length=1053) Species: 28875 (Rotavirus A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKYNLILSEYLSFIYNSQSAVQIPIYYSSNSENATLLSILSYSYDKYNAV
ERKLVKYAKGKPLEADLTVNELDYENNKITSELFPTAEEYTDLLMDPAIL
TSLSSNLNAVMFWLEKHENDVAEKLKIYKRRLDLFTIVASTVNKYGVPRH
NAKYRYEYEVMKDKPYYLVTWANSSIEMLMSVFSHEDYLIARELIVLSYS
NRSTLAKLVSSPMSILVALVDINGTFITNEELELEFSNKYVRAIVPDQTF
DELKQMLDNMRKAGLTDIPKMIQDWLVDCSIEKFPLMAKIYSWSFHVGFR
KQKMLDAALDQLKTEYTEDVDDEMYREYTMLIRDEVVKMLEEPVKHDDHL
LQDSELAGLLSMSSASNGESRQLKFGRKTIFSTKKNMHVMDDMANGRYTP
GIIPPVNVDKPIPLGRRDVPGRRTRIIFILPYEYFIAQHAVVEKMLIYAK
HTREYAEFYSQSNQLLSYGDVTRFLSNNSMVLYTDVSQWDSSQHNTQPFR
KGIIMGLDMLANMTNDARVIQTLNLYKQTQINLMDSYVQIPDGNVIKKIQ
YGAVASGEKQTKAANSIANLALIKTVLSRISNKYSFATKIIRVDGDDNYA
VLQFNTEVTKQMVQDVSNDVRETYARMNTKVKALVSTVGIEIAKRYIAGG
KIFFRAGINLLNNEKKGQSTQWDQAAVLYSNYIVNRLRGFETDREFILTK
IMQMTSVAITGSLRLFPSERVLTTNSTFKVFDSEDFIIEYGTTDDEVYIQ
RAFMSLSSQKSGIADEIAASSTFKNYVSRLSEQLLFSKNNIVSRGIALTE
KAKLNSYAPISLEKRRAQISALLTMLQKPVTFKSSKITINDILRDIKPFF
TVNEAHLPIQYQKFMPTLPDNVQYIIQCIGSRTYQIEDDGSKSAISRLIS
KYSVYKPSIEELYKVISLHENEIQLYLISLGIPKIDADTYVGSKIYSQDK
YRILESYVYNLLSINYGCYQLFDFNSPDLEKLIRIPFKGKIPAVTFILHL
YAKLEVINHAIKNGSWISLFCNYPKSEMIKLWKKMWNITSLRSPYTNANF
FQD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ogy In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		K413 F416 T418 K419 I798 Y842
Binding residue
(residue number reindexed from 1)		K378 F381 T383 K384 I763 Y807
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0019079 viral genome replication
Cellular Component
GO:0044423 virion component

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ogy, PDBe:6ogy, PDBj:6ogy
PDBsum6ogy
PubMed31101900
UniProtG0YZJ9

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