Structure of PDB 6o9u Chain A Binding Site BS02

Receptor Information
>6o9u Chain A (length=283) Species: 188 (Paramagnetospirillum magnetotacticum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRILNSDGSSNITRLGLWLDDHYHDLLTVSWPVFITLITGLYLVTNALFA
LAYLACGDVIENARPGSFTDAFFFSVQTMATIGYGKLIPIGPLANTLVTL
EALCGMLGLAVAASLIYARFTRPTAGVLFSSRMVISDFEGKPTLMMRLAN
LRIEQIIEADVHLVLVRSEISQEGMVFRRFHDLTLTRSRSPIFSLSWTVM
HPIDHHSPIYGETDETLRNSHSEFLVLFTGHHEAFAQNVHARHAYSCDEI
IWGGHFVDVFTTLPDGRRALDLGKFHEIAQHHH
Ligand information
Ligand IDZ3P
InChIInChI=1S/C9H15O7P/c10-7(11)1-4-17(16,5-2-8(12)13)6-3-9(14)15/h1-6H2,(H,10,11)(H,12,13)(H,14,15)
InChIKeyXJGZCDJZBUBTKW-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385OC(=O)CC[P](=O)(CCC(O)=O)CCC(O)=O
ACDLabs 12.01O=C(O)CCP(=O)(CCC(=O)O)CCC(=O)O
OpenEye OEToolkits 2.0.4C(CP(=O)(CCC(=O)O)CCC(=O)O)C(=O)O
FormulaC9 H15 O7 P
Name3,3',3''-phosphoryltripropanoic acid
ChEMBL
DrugBank
ZINCZINC000145743383
PDB chain6o9u Chain A Residue 417 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6o9u A constricted opening in Kir channels does not impede potassium conduction.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		F208 S209 L210 S211 W212 T213 F275 R283
Binding residue
(residue number reindexed from 1)		F193 S194 L195 S196 W197 T198 F260 R268
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005242 inward rectifier potassium channel activity
GO:0042802 identical protein binding
Biological Process
GO:0006813 potassium ion transport
GO:0034220 monoatomic ion transmembrane transport
GO:0034765 regulation of monoatomic ion transmembrane transport
GO:1990573 potassium ion import across plasma membrane
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0034702 monoatomic ion channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6o9u, PDBe:6o9u, PDBj:6o9u
PDBsum6o9u
PubMed32541684
UniProtD9N164|IRK10_PARME Inward rectifier potassium channel Kirbac3.1

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