Structure of PDB 6o7b Chain A Binding Site BS02

Receptor Information
>6o7b Chain A (length=703) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEIDELTALGGLLHDIGKPVQRAGLYSGDHSTQGARFLRDLAENTGRAEY
ELLSLFSENDELMIRRIKELSPERFGLTMEDVLNALWIVYEADNLASPQA
SRPLYSVFNPGKAYPWAELDFEKELPVPGDVFSIRSQDYRELVKRLWEEL
SKAKLRSDRLLPVLEKYLTFVSSVTSEGNIISLYDHMRMTSAIALAMLRA
GCTAGRCRKEKRFLLIEGDFSGIQDFIYRVSTLKYLRARSAYLELIGWDV
VLEILSRLGLTRANVVFNAGGHFMIIAQNTPDAVKELEEIRAKAVEWLYR
EFESDLYLAIEWEPVSGREFGREGNLFAEARKRLKHKLTVRKLKRFGEIK
GLFECNRLVSLLLGFGRTAKNDAGVLVEGPFSGFVPYLQGGRPVGEQILV
KNTLNPGEIPESAQFVPYFVADYFKKDPKGGVATFEELSMASTGTRRLGV
MKGDVDRLGEFFSSMDSPSKLATASRFMDYFFKGYIGAIIEGKFGYIIGD
VPSLRDWPEEPDIVVVYAGGDAFFIVGAWDQIFELAFRVRRAFNAYTGGK
LTLSVGLGYFDERTPIYRMADVVSERLDTAKDEGRNRVFVVGRSRPLDGK
HKLSYEWNHYEELWRTYAPRIYAGNGRLKGKLESKKGLLWKLLEIRELYV
RDPNDVRWAYLTAYLLDLFPELVGIDTKAVERKEPQPVYWVDGVLKIVLM
AVR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6o7b Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		I243 Q244 I247 L266 F290 G293 H295 D521 R524 L525 F529 S542 Y584 G587 D588 S641 K648
Binding residue
(residue number reindexed from 1)		I223 Q224 I227 L243 F267 G270 H272 D454 R457 L458 F462 S475 Y517 G520 D521 S574 K581
Enzymatic activity
Enzyme Commision number 2.7.7.-
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6o7b, PDBe:6o7b, PDBj:6o7b
PDBsum6o7b
PubMed31326272
UniProtB6YWB8|CAS10_THEON CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A) (Gene Name=csm1)

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