Structure of PDB 6nk2 Chain A Binding Site BS02
Receptor Information
>6nk2 Chain A (length=177) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
GPGEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMYSVCNVMS
GDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYA
ESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLT
RKGFYLAFQDIGACVALLSVRVYYKKA
Ligand information
>6nk2 Chain D (length=13) Species:
32630
(synthetic construct) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
WLAYPDSVPYRPK
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
6nk2
Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
N133 Q135
Binding residue
(residue number reindexed from 1)
N109 Q111
Enzymatic activity
Enzyme Commision number
2.7.10.1
: receptor protein-tyrosine kinase.
External links
PDB
RCSB:6nk2
,
PDBe:6nk2
,
PDBj:6nk2
PDBsum
6nk2
PubMed
31015204
UniProt
P29317
|EPHA2_HUMAN Ephrin type-A receptor 2 (Gene Name=EPHA2)
[
Back to BioLiP
]
