Structure of PDB 6nj9 Chain A Binding Site BS02

Receptor Information
>6nj9 Chain A (length=99) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVKALQEASEAYLVALFEDTNLCAIHAKRVTIKPKDIQLARRIRGERA
Ligand information
>6nj9 Chain J (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcggatgtatatatctgacacgtgcctggagactagggagtaatcccct
tggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgcta
gagctgtctacgaccaattgagcggcctcggcaccgggattctcga
Receptor-Ligand Complex Structure
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PDB6nj9 Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Resolution2.96 Å
Binding residue
(original residue number in PDB)		R42 R72 R83 V117 T118
Binding residue
(residue number reindexed from 1)		R6 R36 R47 V81 T82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6nj9, PDBe:6nj9, PDBj:6nj9
PDBsum6nj9
PubMed30765112
UniProtP84233|H32_XENLA Histone H3.2

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