Structure of PDB 6mup Chain A Binding Site BS02

Receptor Information
>6mup Chain A (length=102) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HQHSRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQ
AQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEE
GL
Ligand information
>6mup Chain J (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcgaggaagttcatataaaaggcaaacggaagcattctcagaatattct
ttgtgatgatggagtttcactcacagagctgaacatgccttttgatggag
cagtttccaaatacacttttggtagaatctgcaggtggatatttgat
Receptor-Ligand Complex Structure
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PDB6mup Structure of the Human Core Centromeric Nucleosome Complex.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
R43 R44 R63 K64 P66
Binding residue
(residue number reindexed from 1)
R6 R7 R26 K27 P29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6mup, PDBe:6mup, PDBj:6mup
PDBsum6mup
PubMed31353180
UniProtP49450|CENPA_HUMAN Histone H3-like centromeric protein A (Gene Name=CENPA)

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