Structure of PDB 6mqb Chain A Binding Site BS02

Receptor Information
>6mqb Chain A (length=267) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNPPGLGVPTPQTLQLHSLTH
VIEEKGVKLKLTVTDTPGFGDQINNDNCWDPILGYINEQYEQYLQEEILI
TRQRHIPDTRVHCCVYFVPPTGHCLRPLDIEFLQRLCRTVNVVPVIARAD
SLTMEEREAFRRRIQQNLRTHCIDVYPQMCNDKILNSKLRDRIPFAVVGA
DQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDIT
HNIHYENYRVIRLNESH
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6mqb Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6mqb A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface.
Resolution2.12 Å
Binding residue
(original residue number in PDB)		S63 T89
Binding residue
(residue number reindexed from 1)		S16 T42
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6mqb, PDBe:6mqb, PDBj:6mqb
PDBsum6mqb
PubMed32431830
UniProtQ8IYM1|SEP12_HUMAN Septin-12 (Gene Name=SEPTIN12)

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