Structure of PDB 6m9g Chain A Binding Site BS02

Receptor Information

>6m9g Chain A (length=280) Species: 1393 (Brevibacillus brevis)

QFNPLVYTHGGKLERKSKKDKTASKVFEEFGVMEAYNCWKEASLCIQQRD
KDSVLKLVAALNTYKDAVEPIFDSRLNSAQEVLQPSILEEFFEYLFSRID
SIVGVNIPIRHPAKGYLSLSFNPHNIETLIQSPEYTVRAKDHDFIIGGSA
KLTIQGHGGEGETTNIVVPAVAIECKRYLERNMLDECAGTAERLKRATPY
CLYFVVAEYLKLDDGAPELTEIDEIYILRHQRNSERNKPGFKPNPIDGEL
IWDLYQEVMNHLGKIWWDPNSALQRGKVFN

Ligand information

• Ligand ID: TBR
• InChI: InChI=1S/12BrH.6Ta/h12*1H;;;;;;/q;;;;;;;;;;;;;;;;;+1/p-1
• InChIKey: YWYIQTPPCOBSGN-UHFFFAOYSA-M
• SMILES:
  OpenEye OEToolkits 1.7.0: Br[Ta]123456Br[Ta]17891%10[Ta]22%11(Br7)[Ta]337%12%13([Ta]484([Ta]923(Br%11)(Br1)(Br4)(Br7)Br%12)(Br5)(Br%10)Br%13)Br6
  CACTVS 3.370: Br|1[Ta]|2|3|4|5|Br[Ta]|6|7|89%10|2|Br[Ta]|%11|%12|%13|%14|1|3|6Br|[Ta]|%15|%16|%17|7|%11(Br|[Ta]|%18|4|%12|%15(Br|%13)(Br|%14)|Br[Ta]|5|8|%16|%18(|Br9)(Br)Br|%17)|Br%10
• Formula: Br12 Ta6
• Name: HEXATANTALUM DODECABROMIDE;
  DODECABROMOHEXATANTALUM
• DrugBank: DB04119
• PDB chain: 6m9g Chain A Residue 304

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6m9g Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
• Resolution: 2.35 Å
• Binding residue (original residue number in PDB): K267 F282
• Binding residue (residue number reindexed from 1): K264 F279
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0004519 endonuclease activity

External links

• PDB: RCSB:6m9g, PDBe:6m9g, PDBj:6m9g
• PDBsum: 6m9g
• PubMed: 30395313
• UniProt: Q5D6Y4