Structure of PDB 6m2v Chain A Binding Site BS02

Receptor Information
>6m2v Chain A (length=192) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLV
LAGGYEDDVDNGNYFTYTGSGSSDQKLTNNNRALALNCHSPINEKGAEAE
DWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVKYWPERFLVWRYL
LRRDDTEPEPWTREGKDRTRQLGLTMQYPEGYLEALANKEKS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6m2v Mechanistic insights into recognition of symmetric methylated cytosines in CpG and non-CpG DNA by UHRF1 SRA.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
R448 H450 H455 R457 S458
Binding residue
(residue number reindexed from 1)
R32 H34 H39 R41 S42
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:6m2v, PDBe:6m2v, PDBj:6m2v
PDBsum6m2v
PubMed33359809
UniProtQ8VDF2|UHRF1_MOUSE E3 ubiquitin-protein ligase UHRF1 (Gene Name=Uhrf1)

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