Structure of PDB 6m0x Chain A Binding Site BS02 |
| >6m0x Chain A (length=1032) Species: 322159 (Streptococcus thermophilus LMD-9)
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LVLGLDIGIGSVGVGILNKVTGEIIHKNSRIFPAAQAENNLVRRTNRQGR
RLARRKKHRRVRLNRLFEESGLITDFTKISINLNPYQLRVKGLTDELSNE
ELFIALKNMVKHRGISYKTPGQIQLERYQTYGQLRGDFTVEKDGKKHRLI
NVFPTSAYRSEALRILQTQQEFNPQITDEFINRYLEILTGKRKYYHGPGN
EKSRTDYGRYRTSGETLDNIFGILIGKCTFYPDEFRAAKASYTAQEFNLL
NDLNNLTVPTKLSKEQKNQIINYVKNEKAMGPAKLFKYIAKLLDVADIKG
YRIDKSGKAEIHTFEAYRKMKTLETLDIEQMDRETLDKLAYVLTLNTERE
GIQEALEHEFADGSFSQKQVDELVQFRKANSSIFGKGWHNFSVKLMMELI
PELYETSEEQMTILTRLGYIDEKLLTEEIYNPVVAKSVRQAIKIVNAAIK
EYGDFDNIVIEMARETNEDDEKKAIQKIQKANKDEKDAAMLKAANQYNGK
AELPHSVFHGHKQLATKIRLWHQQGERCLYTGKTISIHDLINNSNQFEVD
AILPLSITFDDSLANKVLVYATANQEKGQRTPYQALDSMDDAWSFRELKA
FVRESKTLSNKKKEYLLTEEDISKFDVIERNLVDTRYASRVVLNALQEHF
RAHKIDTKVSVVRGQFTSQLRRHWGIEKTRDTYHHHAVDALIIAASSQLN
LPYQHFVDTLKSKEFEDSILFSYQVDSKFNRKISDATIYATRQAKVGKDK
ADETYVLGKIKDIYTQDGYDAFMKIYKKDKSKFLMYRHDPQTFEKVIEPI
LENYPNKQINEKGKEVPCNPFLKYKEEHGYIRKYSKKGNGPEIKSLKYYD
SKLGNHIDITPKDSNNKVVLQSVSPWRADVYFNKTTGKYEILGLKYADLQ
FEKGTGTYKISQEKYNDIKKKEGVDSDSEFKFTLYKNDLLLVKDTETKEQ
QLFRFLSRTMPKQKHYVELKPYDKQKFEGGEALIKVLGNVANSGQCKKGL
GKSNISIYKVRTDVLGNQHIIKNEGDKPKLDF |
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| PDB | 6m0x Catalytic-state structure and engineering of Streptococcus thermophilus Cas9 |
| Resolution | 2.561 Å |
Binding residue
(original residue number in PDB) | Y120 Y225 F252 L255 G257 R267 N286 Y337 R338 I339 K341 T383 W424 E445 T451 R512 E513 K520 Q524 Q527 K560 K565 E596 V597 D598 S604 N622 Q623 Q627 F673 Y689 R692 D824 A825 T826 Y828 M1049 Q1052 Y1055 A1080 S1082 K1087 |
Binding residue
(residue number reindexed from 1) | Y117 Y194 F221 L224 G226 R236 N255 Y301 R302 I303 K305 T347 W388 E409 T415 R464 E465 K472 Q476 Q479 K512 K517 E548 V549 D550 S556 N574 Q575 Q579 F625 Y637 R640 D735 A736 T737 Y739 M960 Q963 Y966 A991 S993 K998 |
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