Structure of PDB 6kh5 Chain A Binding Site BS02

Receptor Information
>6kh5 Chain A (length=170) Species: 27405 (Penaeus japonicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASQVRQNYHEDCEASINKQINMELYASYVYLSMAYYFERDDVALPGFAKF
FKESSDEEREHAQTFMKYQNKRGGRIVLQQIAAPSMQEWGTGLEALQAAL
DLEKQVNQSLLELHSTASGNNDPHLTKLLEDEYLEEQVDSIKKIGDMITK
LKRAGPHHGLGEYMFDKELN
Ligand information
Ligand IDNI
InChIInChI=1S/Ni/q+2
InChIKeyVEQPNABPJHWNSG-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ni++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ni+2]
FormulaNi
NameNICKEL (II) ION
ChEMBL
DrugBankDB14204
ZINC
PDB chain6kh5 Chain A Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6kh5 Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes.
Resolution2.294 Å
Binding residue
(original residue number in PDB)		E139 S143
Binding residue
(residue number reindexed from 1)		E136 S140
Annotation score1
Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Gene Ontology
Molecular Function
GO:0004322 ferroxidase activity
GO:0008198 ferrous iron binding
GO:0008199 ferric iron binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:6kh5, PDBe:6kh5, PDBj:6kh5
PDBsum6kh5
PubMed31820500
UniProtT2B7E1

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