Structure of PDB 6jzb Chain A Binding Site BS02

Receptor Information
>6jzb Chain A (length=251) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAK
PGTSPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTT
CHGTGHEKQAHSVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVS
VEASDKFEREGTTIFYNLNLNFVQAALGDTVDIPTVHGDVELVIPEGTQT
GKKFRLRSKGAPSLRGGAVGDQYVTVNVVTPTGLNDRQKVALKEFAAAGD
L
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6jzb Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6jzb Structural insights into the formation of oligomeric state by a type I Hsp40 chaperone.
Resolution2.754 Å
Binding residue
(original residue number in PDB)		C165 C168 C191 C194
Binding residue
(residue number reindexed from 1)		C58 C61 C84 C87
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0031072 heat shock protein binding
GO:0046872 metal ion binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006260 DNA replication
GO:0006457 protein folding
GO:0009408 response to heat
GO:0042026 protein refolding
GO:0051085 chaperone cofactor-dependent protein refolding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6jzb, PDBe:6jzb, PDBj:6jzb
PDBsum6jzb
PubMed32621942
UniProtA0MSU1

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