Structure of PDB 6jwj Chain A Binding Site BS02

Receptor Information
>6jwj Chain A (length=466) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIKELAVDEELAAADGLIPRQKSKLCKHGDRGMCEYCSPLPPWDKEYHEK
NKIKHISFHSYLKKLNENANKKENGSSYISPLSEPDFRINKRCHNGHEPW
PRGICSKCQPSAITLQQQEFRMVDHVEFQKSEIINEFIQAWRYTGMQRFG
YMYGSYSKYDNTPLGIKAVVEAIYEPPQHDEQDGLTMDVEQVKNEMLQID
RQAQEMGLSRIGLIFTDLSDAGAGDGSVFCKRHKDSFFLSSLEVIMAARH
QTRHPNVSKYSEQGFFSSKFVTCVISGNLEGEIDISSYQVSTEAEALVTA
DMISGSTFPSMAYINDTTDERYVPEIFYMKSNEYGITVKENAKPAFPVDY
LLVTLTHGFPNTTNSKFVSSTGFPWSNRQAMGQSQDYQELKKYLFNVASS
GDFNLLHEKISNFHLLLYINSLQILSPDEWKLLIESAVKNEWEESLLKLV
SSAGWQTLVMILQESG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6jwj Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6jwj Structural insights into ubiquitin recognition and Ufd1 interaction of Npl4.
Resolution1.58 Å
Binding residue
(original residue number in PDB)		C137 H139 C145 C148
Binding residue
(residue number reindexed from 1)		C26 H28 C34 C37
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process

View graph for
Biological Process
External links
PDB RCSB:6jwj, PDBe:6jwj, PDBj:6jwj
PDBsum6jwj
PubMed31836717
UniProtP33755|NPL4_YEAST Nuclear protein localization protein 4 (Gene Name=NPL4)

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