Structure of PDB 6jwi Chain A Binding Site BS02

Receptor Information
>6jwi Chain A (length=459) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IKELAVDEELEKEDGLIPRQKSKLCKHGDRGMCEYCSPLPPWDKEYHEKN
KIKHISFHSYLKKLNENANSYISPLSEPDFRINKRCHNGHEPWPRGICSK
CQPSAITLQQQEFRMVDHVEFQKSEIINEFIQAWRYTGMQRFGYMYGSYS
KYDNTPLGIKAVVEAIYEPPQHDEQDGLTMDVEQVKNEMLQIDRQAQEMG
LSRIGLIFTDLSDAGAGDGSVFCKRHKDSFFLSSLEVIMAARHQTRHPNV
SKYSEQGFFSSKFVTCVISGNLEGEIDISSYQVSTEAEALVTADMISGST
FPSMAYINDTTDERYVPEIFYMKSNITVKENAKPAFPVDYLLVTLTHGFP
NTDTETNSKFVSSTGFPWSNRQAMGQSQDYQELKKYLFNVASSGDFNLLH
EKISNFHLLLYINSLQILSPDEWKLLIESAVKNEWEESLLKLVSSAGWQT
LVMILQESG
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain6jwi Chain C Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6jwi Structural insights into ubiquitin recognition and Ufd1 interaction of Npl4.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		L296 T297 M298 D299 L353 M357
Binding residue
(residue number reindexed from 1)		L178 T179 M180 D181 L235 M239
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process

View graph for
Biological Process
External links
PDB RCSB:6jwi, PDBe:6jwi, PDBj:6jwi
PDBsum6jwi
PubMed31836717
UniProtP33755|NPL4_YEAST Nuclear protein localization protein 4 (Gene Name=NPL4)

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