Structure of PDB 6jvw Chain A Binding Site BS02

Receptor Information
>6jvw Chain A (length=260) Species: 627192 (Sphingobium sp. SYK-6) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRLARFDGGRLGVVIGDEIADITALTGADPAQWPDMNMIRLIRDFEGLRG
AIEAALPGLARIPLAQVSLETPVPWPNKIIAYPVNYHAGFFLKPGSALSG
PTDPVVLPAVPGREVHHESELAIIIGKTCRSVAREDWKDVVFGYACLLDM
VVRGRVFRKAYDTFCPVGPWITTADAVNDPATLDMKLWVNDDLRQKANTR
DLVLDIPGMIATASAVMTLQPGDIIATGTPEGVGPVVDGDRIRIVIDQVG
EMAVDVVQGQ
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain6jvw Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6jvw Structural insights into a maleylpyruvate hydrolase from sphingobium sp. SYK-6, a bacterium degrading lignin-derived aryls.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		E132 E134 D163
Binding residue
(residue number reindexed from 1)		E118 E120 D149
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0018773 acetylpyruvate hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6jvw, PDBe:6jvw, PDBj:6jvw
PDBsum6jvw
PubMed31079929
UniProtG2IPX5

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