Structure of PDB 6jfo Chain A Binding Site BS02

Receptor Information

>6jfo Chain A (length=183) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIA
KRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSV
QEAYLPTGEGCLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAI
VFQHEIDHLNGVMFYDHIDKNHPLQPHTDAVEV

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

6jfo Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6jfo Formyl-Met-Ala-Ser bound crystal structure of class II peptide deformylase from methicillin resistant Staphylococcus aureus
Resolution	1.6 Å
Binding residue (original residue number in PDB)	A111 H154 H158
Binding residue (residue number reindexed from 1)	A111 H154 H158
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	G60 Q65 C111 L112 H154 E155 H158
Catalytic site (residue number reindexed from 1)	G60 Q65 C111 L112 H154 E155 H158
Enzyme Commision number	3.5.1.88: peptide deformylase.

Gene Ontology

	Molecular Function
GO:0016787	hydrolase activity
GO:0042586	peptide deformylase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006412	translation
GO:0018206	peptidyl-methionine modification

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Molecular Function

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Biological Process

External links

PDB	RCSB:6jfo, PDBe:6jfo, PDBj:6jfo
PDBsum	6jfo
PubMed
UniProt	P68826\|DEF_STAAU Peptide deformylase (Gene Name=def)

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