Structure of PDB 6jbc Chain A Binding Site BS02

Receptor Information
>6jbc Chain A (length=295) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLIRAFIPAHITAFFVPVFHEEPLKAGSLGAGVNLSKGTNVFASIETGTL
ERHIHVAFNGEPVKREEAEITYYVAEKLVPKDFLGEVEVWQYFDFPNGYG
FGNSAGGALGTALALSYAFGGTWLRAAQLAHEAEVKHKGGLGDVIGQLAG
GIEVRIKPGGPGIGVTDNLFFEDYKVLVVPLGRLSDGDVVKAIEVEGRKA
LEELLKEPKPERMMVLARNFAEKTGLLPGELSEIARELDKVLKNPSSMIM
LGKGLFALVRDEEAEKAKQLLSDMNLPYDIAEIYTERPKVGRWVG
Ligand information
Ligand IDGOL
InChIInChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
InChIKeyPEDCQBHIVMGVHV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C(C(CO)O)O
ACDLabs 12.01
CACTVS 3.370		OCC(O)CO
FormulaC3 H8 O3
NameGLYCEROL;
GLYCERIN;
PROPANE-1,2,3-TRIOL
ChEMBLCHEMBL692
DrugBankDB09462
ZINCZINC000000895048
PDB chain6jbc Chain A Residue 803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6jbc Crystal structure of pantoate kinase from Thermococcus kodakarensis.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		T12 G140 L141 G142
Binding residue
(residue number reindexed from 1)		T12 G140 L141 G142
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.1.169: pantoate kinase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0015937 coenzyme A biosynthetic process
GO:0016310 phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6jbc, PDBe:6jbc, PDBj:6jbc
PDBsum6jbc
PubMed31697438
UniProtQ5JHF1|POK_THEKO Pantoate kinase (Gene Name=TK2141)

[Back to BioLiP]