Structure of PDB 6j5y Chain A Binding Site BS02

Receptor Information
>6j5y Chain A (length=233) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NHLFAPEAPVSLTIHGSDQTFPVRRVYCVGRNYAAHAREMGFDPEREPPF
FFCKPADAVVPVAAGSTLELAYPSQTGNYHYEIELVAAIGKGGCDIPLEQ
AEEHVWGYAVGLDMTRRDLQMRMREMGRPWEIGKAFDRSAPIGPLYPASQ
VGHPRHAAISLQVDGEDRQRSDIDQLIWSVAETVSYLSRFFELRPGDLVF
TGTPEGVGAVERGERMLGAIDGLGELSVRVVLE
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain6j5y Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6j5y Sequence, structure and function-based classification of the broadly conserved FAH superfamily reveals two distinct fumarylpyruvate hydrolase subfamilies.
Resolution1.98 Å
Binding residue
(original residue number in PDB)		E83 E85 D114
Binding residue
(residue number reindexed from 1)		E82 E84 D113
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0018773 acetylpyruvate hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6j5y, PDBe:6j5y, PDBj:6j5y
PDBsum6j5y
PubMed31657110
UniProtQ9I111

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