Structure of PDB 6i5j Chain A Binding Site BS02

Receptor Information
>6i5j Chain A (length=168) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMQAARLAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSD
YLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYY
VQMCKDKRGPEAPRNGTVHLYLTKPLYTSAPSLQHLCRLTINKCTGAIWG
LPLPTRLKDYLEEYKFQV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6i5j Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Y128 M132 X133 K136 R137 T147 V148 H149
Binding residue
(residue number reindexed from 1)		Y99 M103 X104 K107 R108 T117 V118 H119
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0035556 intracellular signal transduction

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Biological Process
External links
PDB RCSB:6i5j, PDBe:6i5j, PDBj:6i5j
PDBsum6i5j
PubMed31182716
UniProtO14508|SOCS2_HUMAN Suppressor of cytokine signaling 2 (Gene Name=SOCS2)

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