Structure of PDB 6i3t Chain A Binding Site BS02

Receptor Information

>6i3t Chain A (length=148) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RPESELIRQSWRVVSRSPLEHGTVLFARLFALEPSLLPLFQYNGRQFSSP
EDSLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLTSLGRKHRAVGVR
LSSFSTVGESLLYMLEKSLGPDFTPATRTAWSRLYGAVVQAMSRGWDG

Ligand information

InChI=1S/CO/c1-2

UGFAIRIUMAVXCW-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04	[O+]#[C-]
CACTVS 3.341 OpenEye OEToolkits 1.5.0	[C-]#[O+]

Formula

C O

Name

CARBON MONOXIDE

PDB chain

6i3t Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6i3t Ligand pathways in neuroglobin revealed by low-temperature photodissociation and docking experiments.
Resolution	2.0 Å
Binding residue (original residue number in PDB)	F28 H64 V68
Binding residue (residue number reindexed from 1)	F26 H62 V66
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.7.-.-

Gene Ontology

	Molecular Function
GO:0005092	GDP-dissociation inhibitor activity
GO:0005344	oxygen carrier activity
GO:0005515	protein binding
GO:0016491	oxidoreductase activity
GO:0019825	oxygen binding
GO:0020037	heme binding
GO:0046872	metal ion binding
GO:0098809	nitrite reductase activity

	Biological Process
GO:0015671	oxygen transport
GO:0071456	cellular response to hypoxia

	Cellular Component
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix
GO:0005829	cytosol

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Cellular Component

External links

PDB	RCSB:6i3t, PDBe:6i3t, PDBj:6i3t
PDBsum	6i3t
PubMed	31576217
UniProt	Q9ER97\|NGB_MOUSE Neuroglobin (Gene Name=Ngb)

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