Structure of PDB 6hso Chain A Binding Site BS02

Receptor Information
>6hso Chain A (length=412) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPF
PASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIP
CGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGE
CVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLL
PGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVI
ITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVR
KIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLD
PRPEYHRCILTWHHQEPLPWAQSTGLMSMRSANGLLMLPPKTEQYVELHK
GEVVDVMVIGRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hso Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		R660 E684 K724
Binding residue
(residue number reindexed from 1)		R342 E366 K400
Enzymatic activity
Enzyme Commision number 2.10.1.1: molybdopterin molybdotransferase.
2.7.7.75: molybdopterin adenylyltransferase.
Gene Ontology
Biological Process
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
GO:0032324 molybdopterin cofactor biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:6hso, PDBe:6hso, PDBj:6hso
PDBsum6hso
PubMed30704910
UniProtQ03555|GEPH_RAT Gephyrin (Gene Name=Gphn)

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