Structure of PDB 6hau Chain A Binding Site BS02

Receptor Information
>6hau Chain A (length=273) Species: 10383 (Herpesvirus saimiri (strain 11)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPLLKLFDISILPKSGEPKLFLPVPSLPCQEAEKTNDKYVLAMAQRAMHD
VPISSKQLTANLLPVKFKPLLSIVRYTPNYYYWVSMRKETIASANLCTVA
AFLDESLCWGQQYLKNDFIFSENGKDIILDTSSALLSQLVHKIKMLPFCH
CLMQTTPQDHIVKQVCYLIASNNRILDAVRYLQTSVIKSPIVLLLAYAVC
LPAAIICTKNETQLYSHCMRILKEYRPGDVMNILHESLTQHLNKCPSSTC
AYTTRAIVGTKANTTGLFFLPTQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6hau Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hau Structural identification of conserved RNA binding sites in herpesvirus ORF57 homologs: implications for PAN RNA recognition.
Resolution1.86 Å
Binding residue
(original residue number in PDB)
C293 H385 C389 C394
Binding residue
(residue number reindexed from 1)
C149 H241 C245 C250
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:6hau, PDBe:6hau, PDBj:6hau
PDBsum6hau
PubMed30462297
UniProtP13199|ICP27_SHV21 mRNA export factor ICP27 homolog (Gene Name=EJRF1)

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