Structure of PDB 6gux Chain A Binding Site BS02

Receptor Information

>6gux Chain A (length=241) Species: 35743 (Halorubrum sodomense) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QAGYDLLGDGRPETLWLGIGTLLMLIGTFYFLVRGWGVTDKDAREYYAVT
ILVPGIASAAYLSMFFGIGLTEVTVGGEMLDIYYARYADWLFTTPLLLLD
LALLAKVDRVTIGTLVGVDALMIVTGLIGALSHTAIARYSWWLFSTICMI
VVLYFLATSLRSAAKERGPEVASTFNTLTALVLVLWTAYPILWIIGTEGA
GVVGLGIETLLFMVLDVTAKVGFGFILLRSRAILGDTEAPE

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

6gux Chain A Residue 713 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6gux Structures of the archaerhodopsin-3 transporter reveal that disordering of internal water networks underpins receptor sensitization.
Resolution	1.3 Å
Binding residue (original residue number in PDB)	D46 D48 L240
Binding residue (residue number reindexed from 1)	D40 D42 L234
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005216	monoatomic ion channel activity
GO:0009881	photoreceptor activity

	Biological Process
GO:0006811	monoatomic ion transport
GO:0007602	phototransduction
GO:1902600	proton transmembrane transport

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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Molecular Function

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Cellular Component

External links

PDB	RCSB:6gux, PDBe:6gux, PDBj:6gux
PDBsum	6gux
PubMed	33504778
UniProt	P96787\|BACR3_HALSD Archaerhodopsin-3 (Gene Name=aop3)

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