Structure of PDB 6fq8 Chain A Binding Site BS02

Receptor Information
>6fq8 Chain A (length=95) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRG
Ligand information
>6fq8 Chain J (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ctggagaatcccggtgccgaggccgctcaattggtcgtagacagctctag
caccgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaagg
ggattactccctagtctccaggcacgtgtcagatatatacatcctgt
Receptor-Ligand Complex Structure
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PDB6fq8 Structural rearrangements of the histone octamer translocate DNA.
Resolution4.8 Å
Binding residue
(original residue number in PDB)
H39 R40 Y41 P43 G44 V46 K56 R63 K64 L65 R69 D81 R83
Binding residue
(residue number reindexed from 1)
H2 R3 Y4 P6 G7 V9 K19 R26 K27 L28 R32 D44 R46
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6fq8, PDBe:6fq8, PDBj:6fq8
PDBsum6fq8
PubMed29626188
UniProtP02302|H3C_XENLA Histone H3.3C (Gene Name=h3-5)

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