Structure of PDB 6f3h Chain A Binding Site BS02

Receptor Information
>6f3h Chain A (length=762) Species: 5478 (Nakaseomyces glabratus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLSFDPAELLRTSLNVGDIVLLKQCTSELTMCVNLPQSTTDPRYTFAKKD
GTLVYAMKNSVILRIPKPVLTRQLIVSFTLATFTKFAWTQLPIVLKKLEL
IHRYLQDSRGSKHVNFMSLVRIIKNLNIKEATDAIDAYVRKVIDESMSNK
SIDPTTLLATYWGVREQQQNNLWGSVYTNTALLSPTTVAVLPLKKAHLFY
QEVITRLESNDYQEIKAFAKLVNDKDYHSIAKRYDYIRTLLNDYAAGNIE
ENAVLTTIISKIFRHIDMYRDQDVTRSLCGKLLVEISPQSNSSNFILGNW
DLNIPKSGISSVEQKLYDTAMPTIVTDRYDFGDMPVFCIDSEDAHEINDG
ISIEELDGVRSRIHIHIADPAGLFPESFDYTKSGISDDVLRVSLKRAFTT
YLPDLVVPMLPKSFCNRADLGKHDRKTETISFSFELVNKEDGGLHVDYDT
FQVRLGIVSNFPKVTYDKVDSILNGDDNSLPSKQKKQLELLHTLATKLLH
KRIHDDNAVVFGDGFNKGLVSLSPDDELCIPTFYDQSQTKSTLLVSEFMI
LTNKLCAAFFQENKIPGVYRCYNGLNLGNQAKAQFELLKENIKLGKLPSL
KDITKISSQLSSSFYSPFPLPHKMIGNTAYLTVTSPMRRGPDLINHLQLH
RFLKKLPLCFKQEYLDQYVWSFQARADILKIFQRHSSTYWTLKHLEQSGK
THDVIVTSVPQNGTVNCLFPEYSYARGTLKLDPAMIPRIGDTIRHCKVES
IHPLDGILTLTH
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6f3h Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6f3h Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components.
Resolution2.703 Å
Binding residue
(original residue number in PDB)		D469 D478
Binding residue
(residue number reindexed from 1)		D340 D349
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008859 exoribonuclease II activity
GO:0046872 metal ion binding
Biological Process
GO:0000957 mitochondrial RNA catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0045025 mitochondrial degradosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6f3h, PDBe:6f3h, PDBj:6f3h
PDBsum6f3h
PubMed29311576
UniProtQ6FJE0

[Back to BioLiP]