Structure of PDB 6e5x Chain A Binding Site BS02

Receptor Information
>6e5x Chain A (length=127) Species: 128951 (Ebola virus - Zaire (1995)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKITLLTLIKTAEHWARQDIRTIEDSKLRALLTLCAVMTRKFSKSQLSLL
CETHLRREGLGQDQAEPVLEVYQRLHSDKGGSFEAALWQQWDRQSLIMFI
TAFLNIALQLPCESSAVVVSGLRTLVP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6e5x Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6e5x Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication.
Resolution1.5 Å
Binding residue
(original residue number in PDB)
A155 N244
Binding residue
(residue number reindexed from 1)
A16 N105
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:6e5x, PDBe:6e5x, PDBj:6e5x
PDBsum6e5x
PubMed30550789
UniProtQ77DJ5|VP30_EBOZ5 Transcriptional activator VP30 (Gene Name=VP30)

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