Structure of PDB 6due Chain A Binding Site BS02

Receptor Information
>6due Chain A (length=737) Species: 507601 (Toxoplasma gondii GT1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YKGFQIWTDLAPSVKEEPDLMFAKCIVQAGTDKGNLTCVQIDPPGFDEPF
EVPQANAWNVNSLIDPMTYGDIGMLPHTNIPCVLDFLKVRFMKNQIYTTA
DPLVVAINPFRDLGNTTLDWIVRYRDTFDLSKLAPHVFYTARRALDNLHA
VNKSQTIIVSGESGAGKTEATKQIMRYFAAAKTGSMDLRIQNAIMAANPV
LEAFGNAKTIRNNNSSRFGRFMQLDVGREGGIKFGSVVAFLLEKSRVLTQ
DEQERSYHIFYQMCKGADAAMKERFHILPLSEYKYINPLCLDAPGIDDVA
EFHEVCESFRSMNLTEDEVASVWSIVSGVLLLGNVEVTATKDGGIDDAAA
IEGKNLEVFKKACGLLFLDAERIREELTVKVSYAGNQEIRGRWKQEDGDM
LKSSLAKAMYDKLFMWIIAVLNRSIKPPGGFKIFMGMLDIFGFEVFKNNS
LEQFFINITNEMLQKNFVDIVFDRESKLYRDEGVSSKELIFTSNAEVIKI
LTAKNNSVLAALEDQCLAPGGSDEKFLSTCKNALKGTTKFKPAKVSPNIN
FLISHTVGDIQYNAEGFLFKNKDVLRAEIMEIVQQSKNPVVAQLFAGIVG
QLIGSQFLSQLQSLMELINSTEPHFIRCIKPNDTKKPLDWVPSKMLIQLH
ALSVLEALQLRQLGYSYRRPFKEFLFQFKFIDLSASENPNLDPKEAALRL
LKSSKLPSEEYQLGKTMVFLKQTGAKELTQIQRECLS
Ligand information
Ligand IDALF
InChIInChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4
InChIKeyUYOMQIYKOOHAMK-UHFFFAOYSA-J
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al-](F)(F)F
FormulaAl F4
NameTETRAFLUOROALUMINATE ION
ChEMBL
DrugBankDB04444
ZINC
PDB chain6due Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6due Structural and mechanistic insights into the function of the unconventional class XIV myosin MyoA fromToxoplasma gondii.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		S195 K199 N244 S247 S248 F473 G474
Binding residue
(residue number reindexed from 1)		S163 K167 N212 S215 S216 F441 G442
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000146 microfilament motor activity
GO:0003774 cytoskeletal motor activity
GO:0003779 actin binding
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0051015 actin filament binding
Biological Process
GO:0007015 actin filament organization
GO:0030050 vesicle transport along actin filament
Cellular Component
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
GO:0016459 myosin complex
GO:0031982 vesicle

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Molecular Function
View graph for
Biological Process
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Cellular Component
External links
PDB RCSB:6due, PDBe:6due, PDBj:6due
PDBsum6due
PubMed30348763
UniProtS7W634

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