Structure of PDB 6dsy Chain A Binding Site BS02

Receptor Information
>6dsy Chain A (length=577) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AFTLADRVTEEMLADKAALVVEVVEENYHDAPIVGIAVVNEHGRFFLRPE
TALADPQFVAWLGDETKKKSMFDSKRAAVALKWKGIELCGVSFDLLLAAY
LLDPAQGVDDVAAAAKMKQYEAVRPDEAVYGKGAKRAVPDEPVLAEHLVR
KAAAIWALERPFLDELRRNEQDRLLVELEQPLSSILAEMEFAGVKVDTKR
LEQMGEELAEQLRTVEQRIYELAGQEFNINSPKQLGVILFEKLQLPVLKK
TKTGYSTSADVLEKLAPYHEIVENILHYRQLGKLQSTYIEGLLKVVRPDT
KKVHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFVPSESDWLI
FAADYSQIELRVLAHIAEDDNLMEAFRRDLDIHTKTAMDIFQVSEDEVTP
NMRRQAKAVNFGIVYGISDYGLAQNLNISRKEAAEFIERYFESFPGVKRY
MENIVQEAKQKGYVTTLLHRRRYLPDITSRNFNVRSFAERMAMNTPIQGS
AADIIKKAMIDLNARLKEERLQARLLLQVHDELILEAPKEEMERLCRLVP
EVMEQAVTLRVPLKVDYHYGSTWYDAK
Ligand information
Receptor-Ligand Complex Structure
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PDB6dsy Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Resolution1.98 Å
Binding residue
(original residue number in PDB)		N527 S530 K532 S585 T586 L610 T619 I716 S717 Y719 N782 F786 R789
Binding residue
(residue number reindexed from 1)		N228 S231 K233 S286 T287 L311 T320 I417 S418 Y420 N483 F487 R490
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004518 nuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0006302 double-strand break repair
GO:0006974 DNA damage response
GO:0071897 DNA biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6dsy, PDBe:6dsy, PDBj:6dsy
PDBsum6dsy
PubMed30338759
UniProtE1C9K5

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