Structure of PDB 6djx Chain A Binding Site BS02

Receptor Information
>6djx Chain A (length=317) Species: 27457 (Bactrocera dorsalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YLGGSLSIYIKTNTGRTLSVNLEPQWDIKNVKEIVAPQLGLQPEEVKIIF
AGKELSDATTIQECDLGQQSILHAIRSRHFFVHCAQCNKLCKGKLRVRCS
LCKGGAFTVHRDPECWDDVLKPRRITGHCESQEIACFDNETGDPPFTEFY
FKCGEHVSGGEKDFAAPLNLIKINIKDVPCLACTEVSETVLVFPCESKHV
TCLECFEQYCRSRLSERQFMPHPDIGYTLPCPAGCENSFIEEIHHFKLLS
REEYARYQRFATEEYVLQAGGVLCPQPGCGMGLLVEPECKKVTCQNGCGY
VFCRNCLQGYHLGDCLP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6djx Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6djx Mechanism of parkin activation by phosphorylation.
Resolution4.801 Å
Binding residue
(original residue number in PDB)		C177 C180 C246 H249
Binding residue
(residue number reindexed from 1)		C84 C87 C153 H156
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.31: RBR-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0008270 zinc ion binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6djx, PDBe:6djx, PDBj:6djx
PDBsum6djx
PubMed29967542
UniProtA0A034W4L8

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