Structure of PDB 6dcr Chain A Binding Site BS02

Receptor Information
>6dcr Chain A (length=639) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPVAHVALPVPLPRTFDYLLPEGMTVKAGCRVRVPFGKQQERIGIVVSVS
DASELPLNELKAVVEVLDSEPVFTHSVWRLLLWAADYYHHPIGDVLFHAL
PILLRQGRPAANADWRTNYAVSLRLNTEQATAVGAIHSAADTFSAWLLAG
VTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVE
VLHSGLNDSERLSAWLKAKNGEAAIVIGTRSALFTPFKNLGVIVIDEEHD
SSYKQQEGWRYHARDLAVYRAHSEQIPIILGSATPALETLCNVQQKKYRL
LRLTRPAIQHVLDLKGQKVQAGLAPALITRMRQHLQADNQVILFLNRRGF
APALLCHDCGWIAECPRCDHYYTLHQAQHHLRCHHCDSQRPVPRQCPSCG
STHLVPVGLGTEQLEQTLAPLFPGVPISRIDRDTTSHRGGARILIGTQML
AKGHHFPDVTLVALLDVDGALFSADFRSAERFAQLYTQVAGRAGRAGKQG
EVVLQTHHPEHPLLQTLLYKGYDAFAEQALAERRMMQLPPWTSHVIVRAE
DHNNQHAPLFLQQLRNLILSSPLADEKLWVLGPVPALAPKRGGRWRWQIL
LQHPSRVRLQHIINGTLALINTIPDSRKVKWVLDVDPIE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6dcr Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6dcr Structure-specific DNA replication-fork recognition directs helicase and replication restart activities of the PriA helicase.
Resolution1.978 Å
Binding residue
(original residue number in PDB)		C445 C448 C463 C466
Binding residue
(residue number reindexed from 1)		C365 C368 C383 C386
Annotation score4
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication
GO:0032508 DNA duplex unwinding

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Molecular Function
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Biological Process
External links
PDB RCSB:6dcr, PDBe:6dcr, PDBj:6dcr
PDBsum6dcr
PubMed30201718
UniProtP17888|PRIA_ECOLI Primosomal protein N' (Gene Name=priA)

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