Structure of PDB 6dbr Chain A Binding Site BS02

Receptor Information
>6dbr Chain A (length=550) Species: 7955,83333 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKE
LLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDVPADTISRRFRY
DVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEK
HGSGPAVPEKAVRFSFTIMSISIRLEGEDDGITIFQEQKPNSELSCRPLC
LMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTG
YDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLER
YEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYK
IFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARR
LMTREAVEAVCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQL
CQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAW
ASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAH
Ligand information
Receptor-Ligand Complex Structure
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PDB6dbr DNA melting initiates the RAG catalytic pathway.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		G623 D624 S626 K628 R991
Binding residue
(residue number reindexed from 1)		G145 D146 S148 K150 R513
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0005515 protein binding
GO:0015144 carbohydrate transmembrane transporter activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
GO:1901982 maltose binding
Biological Process
GO:0006974 DNA damage response
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0033151 V(D)J recombination
GO:0034219 carbohydrate transmembrane transport
GO:0034289 detection of maltose stimulus
GO:0042956 maltodextrin transmembrane transport
GO:0055085 transmembrane transport
GO:0060326 cell chemotaxis
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:1990060 maltose transport complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6dbr, PDBe:6dbr, PDBj:6dbr
PDBsum6dbr
PubMed30061602
UniProtO13033|RAG1_DANRE V(D)J recombination-activating protein 1 (Gene Name=rag1);
P0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE)

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