Structure of PDB 6d95 Chain A Binding Site BS02

Receptor Information
>6d95 Chain A (length=758) Species: 349102 (Cereibacter sphaeroides ATCC 17025) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RQLVSNGFEVNLPDQVEVIVRDLPDPSKVKEERTRLMGYWFVHWFDGKLF
HLRIKAGGPNVDGEHRAIRTAEHPWLLRARLDDALEEALPKYAAVKKRPF
TFLAQKDELIDAAATAAGLSHRLLNSFKVIPRFALSPKIYEPVDGTTRVG
VFVTIGMRYDIEASLRDLLEAGIDLRGMYVVRRKRQPGERGLLGRVRAIS
DDMVQLFEETDLASVNVNDAKLEGSKENFTRCLSALLGHNYKKLLNALDD
QEAGYRTGPRFDDAVRRMGEFLAKKPIRLADNINAQVGDRIVFSNEGQAR
NVRLAPKVEYVFDRTGAKSAEYAWRGLSQFGPFDRPSFANRSPRILVVYP
SSTQGKVENFLSAFRDGMGSNYSGFSKGFVDLMGLTKVEFVMCPVEVSSA
DRNGAHTKYNSAIEDKLAGAGEVHAGIVVLFEDHARLPDDRNPYIHTKSL
LLTLGVPTQQVRMPTVLLEPKSLQYTLQNFSIATYAKLNGTPWTVNHDKA
INDELVVGMGLAELSGSRTEKRQRFVGITTVFAGDGSYLLGNVSKECEYE
GYSDAIRESMTGILRELKKRNNWRPGDTVRVVFHAHRPLKRVDVASIVFE
CTREIGSDQNIQMAFVTVSHDHPFVLIDRSERGLEAYKGSTARKGVFAPP
RGAISRVGRLTRLLAVNSPQLIKRANTPLPTPLLVSLHPDSTFKDVDYLA
EQALKFTSLSWRSTLPAATPVTIFYSERIAELLGRLKSIPNWSSANLNIK
LKWSRWFL
Ligand information
Receptor-Ligand Complex Structure
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PDB6d95 Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		P45 R52 H62 W63 R97 K157 K245 E246 T249 Y260 Y341 R455 Y494 L530 A531 E532 H605 S638 H639 D640 H641 Q689 L690 R693
Binding residue
(residue number reindexed from 1)		P26 R33 H43 W44 R78 K138 K226 E227 T230 Y241 Y322 R436 Y475 L511 A512 E513 H586 S619 H620 D621 H622 Q670 L671 R674
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004520 DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0044355 clearance of foreign intracellular DNA

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Molecular Function
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Biological Process
External links
PDB RCSB:6d95, PDBe:6d95, PDBj:6d95
PDBsum6d95
PubMed29996105
UniProtA4WYU7|AGO_CERS5 Protein argonaute (Gene Name=ago)

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