Structure of PDB 6cil Chain A Binding Site BS02

Receptor Information
>6cil Chain A (length=585) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQG
RGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAE
KVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRF
RYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSE
KEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDH
ETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREV
EGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPY
HESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEV
YKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDA
VCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQR
FAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGQSGNKLFRRFR
KMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6cil Cracking the DNA Code for V(D)J Recombination.
Resolution4.15 Å
Binding residue
(original residue number in PDB)		R440 A441 H445 I846 M847 R848 N850 N852
Binding residue
(residue number reindexed from 1)		R33 A34 H38 I431 M432 R433 N435 N437
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6cil, PDBe:6cil, PDBj:6cil
PDBsum6cil
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

[Back to BioLiP]