Structure of PDB 6bv8 Chain A Binding Site BS02

Receptor Information
>6bv8 Chain A (length=472) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPEALLKQKLDMCSKKGDVLEALRLYDEARRNGVQLSQYHYNVLLYVCSL
AEAATESSPNPGLSRGFDIFKQMIVDKVVPNEATFTNGARLAVAKDDPEM
AFDMVKQMKAFGIQPRLRSYGPALFGFCRKGDADKAYEVDAHMVESEVVP
EEPELAALLKVSMDTKNADKVYKTLQRLRDLVRQVSKSTFDMIEEWFKSE
VATKTGVKKWDVKKIRDAVVSGGGGWHGQGWLGTGKWNVKRTEMDENGVC
KCCKEKLVCIDINPVETETFAASLTRLACEREVKANFNQFQEWLERHGPF
DAVIDGANMGLVNQRSFSFFQLNNTVQRCQQISPSKRLPLVILHKSRVAT
YPKNRALLEKWKNAGALYATPPGSNDDWYWLYAAVSCKCLLVTNDEMRDH
LFQLLGNSFFPRWKEKHQVRISVTREDGLKLNMPPPYSIVIQESEDGTWH
VPMSVEDDLQTSRQWLCAKRSK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6bv8 Chain A Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6bv8 Inhibition of protein-only RNase P with Gambogic acid and Juglone
Resolution2.1 Å
Binding residue
(original residue number in PDB)		C344 C347 H548 C565
Binding residue
(residue number reindexed from 1)		C250 C253 H450 C467
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.26.5: ribonuclease P.
External links
PDB RCSB:6bv8, PDBe:6bv8, PDBj:6bv8
PDBsum6bv8
PubMed
UniProtQ66GI4|PRRP1_ARATH Proteinaceous RNase P 1, chloroplastic/mitochondrial (Gene Name=PRORP1)

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