Structure of PDB 6bqz Chain A Binding Site BS02

Receptor Information

>6bqz Chain A (length=215) Species: 470 (Acinetobacter baumannii)

HHHLPAEEQLALIQRGTHEIISEEDLLKKLKENRPLKIKAGFDPTAPDLH
LGHTVLINKLKTFQDLGHEVTFLIGDYTAMIGDPTRPPLSREQVEANAKT
YQEQVFKILDPNKTKVRFNSEWFNQKSAADLIQLASQQTVSRMLERDDFT
KRYNNHQPIAIHEFLYPLVQGYDSIALEADVELGGTDQTFNLLMGRTLQS
RYGQESQVCITVPIL

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 6bqz Chain A Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6bqz Crystal Structure of Tyrosine-tRNA Synthetase from Acinetobacter baumannii with bound L-Tyrosine
• Resolution: 2.3 Å
• Binding residue (original residue number in PDB): R129 F130 E133
• Binding residue (residue number reindexed from 1): R117 F118 E121
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): T52 H57 H60 R98 Q182 D199
• Catalytic site (residue number reindexed from 1): T45 H50 H53 R86 Q170 D187
• Enzyme Commision number: 6.1.1.1: tyrosine--tRNA ligase.

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0003723 RNA binding
• GO:0004812 aminoacyl-tRNA ligase activity
• GO:0004831 tyrosine-tRNA ligase activity
• GO:0005524 ATP binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation
• GO:0006418 tRNA aminoacylation for protein translation
• GO:0006437 tyrosyl-tRNA aminoacylation
• GO:0043039 tRNA aminoacylation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:6bqz, PDBe:6bqz, PDBj:6bqz
• PDBsum: 6bqz
• UniProt: B0VML7